Tailoring size and release kinetics of κ/ι-hybrid carrageenan microgels via a surfactant-assisted technique

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dc.contributor.affiliationPontificia Universidad Católica del Perú. Departamento de Ingeniería Mecánica
dc.contributor.authorRodriguez, S.
dc.contributor.authorTorres, F.G.
dc.contributor.authorGonzales, K.N.
dc.contributor.authorTroncoso, O.P.
dc.contributor.authorFernández-García, M.
dc.contributor.authorLópez, D.
dc.date.accessioned2026-03-13T17:00:20Z
dc.date.issued2021
dc.description.abstractκ/ι-Hybrid carrageenan microgels were prepared to be used as drug delivery systems. A surfactant-assisted microemulsion technique was used. Tween® 80 was used as surfactant and enrofloxacin was used as a model drug. The results showed that the amount of surfactant used during processing determines the size of the microgels as well as the amount of enrofloxacin that can be loaded. At low surfactant content, the initial burst release effect is dominant whereas at high surfactant content the burst release effect is negligible and the Fickian diffusion mechanism is dominant.
dc.description.sponsorshipFunding: The Vice-Rectorate for Research (VRI-PUCP) of the Pontificia Universidad Catolica del Peru and the National Council of Science, Technology and Technological Innovation (CONCYTEC-FONDECYT) are greatly acknowledged for financial support. The Institute of Polymer Science and Technology of the Spanish Council for Scientific Research (ICTP-CSIC, Madrid, Spain) is acknowledged for experimental assistance.
dc.identifier.doihttps://doi.org/10.1080/00914037.2020.1716225
dc.identifier.urihttp://hdl.handle.net/20.500.14657/206597
dc.language.isoeng
dc.publisherBellwether Publishing
dc.relation.ispartofurn:issn:0091-4037
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.sourceInternational Journal of Polymeric Materials and Polymeric Biomaterials; Vol. 70, Núm. 5 (2021)
dc.subjectPulmonary surfactant
dc.subjectDiffusion
dc.subjectChemical engineering
dc.subjectMicroemulsion
dc.subjectNonionic surfactant
dc.subjectKinetics
dc.subjectChemistry
dc.subjectMaterials science
dc.subjectCarrageenan
dc.subjectEnrofloxacin
dc.subjectChromatography
dc.subjectThermodynamics
dc.subject.ocdehttps://purl.org/pe-repo/ocde/ford#2.04.00
dc.titleTailoring size and release kinetics of κ/ι-hybrid carrageenan microgels via a surfactant-assisted technique
dc.typehttp://purl.org/coar/resource_type/c_6501
dc.type.otherArtículo
dc.type.versionhttps://vocabularies.coar-repositories.org/version_types/c_970fb48d4fbd8a85/

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