Revista de Química. Vol. 32 Núm. 2 (2018)

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Evolución Dirigida, o cómo crear enzimas para fines industriales
(Pontificia Universidad Católica del Perú, 2019-02-22) Salas, Paloma F.
For decades, synthetic chemists have sought to make industrial-scale catalysts as efficient and exceptionally selective as enzymes are in biological systems but, unfortunately, this task has proven evasive. Efforts then focused on making enzymes useful for the industry, and protein engineering had the task of adapting natural enzymes to work in conditions of industrial-scale processes. The approach called directed evolution is one of the models used to carry this out. Inspired by the natural evolution of species, this model proposes to evolve enzymes in an accelerated way, within the laboratory, in such a way that the manipulated enzyme exhibits the properties desired for its industrial application. Directed evolution is responsible, for example, for the industrial-scale production of enzymes included in household detergents and of the enzymes used by the pharmaceutical industry for the generation of intermediates, which are synthesized by microorganisms that express the mutated enzyme evolved in the laboratory. Today, these enzymes, some in industrial use and many others still in the exploratory stage, can catalyze very efficiently synthetic processes that form even non-natural compounds such as organosilanes and organoboranes.
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2018, resumen de un año de gratos recuerdos y éxitos para la OPQ
(Pontificia Universidad Católica del Perú, 2019-02-26) Chong Cáceres, Miguel Angel; Ortega-San-Martin, Luis
The XXIII Peruvian Chemistry Olympiad was held in 2018 with a historic record of participants. On the other hand, Peruvian students had an outstanding performance in the events carried out internationally, both in Bratislava and Prague (50th International Olympiad, IChO) and in San Salvador, Republic of El Salvador (23th Iberoamerican Olympiad, OIAQ). For the first time, a Peruvian student won a silver medal at the IChO.
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La quinina, el símbolo de la XXII Olimpiada Iberoamericana de Química-2017
(Pontificia Universidad Católica del Perú, 2019-04-04) Nakamatsu, Javier; Gonzales Gil, Patricia
Quinine, present in the bark of the cinchona tree, native to the South American Andes, is one of the natural medicines that has saved more lives in the history of humanity. Its economic importance, as a treatment for malaria, generated a search for its synthetic route. This promoted the development of organic synthesis and marked the beginning of industrial organic chemistry. Quinine, a compound so connected not only with the history of Peru but also with that of organic synthesis, was highlighted in the XXII Ibero-American Chemistry Olympiad-2017.
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El renacimiento de la electroquímica
(Pontificia Universidad Católica del Perú, 2018-12-06) Leidinger, Walter; Weber, Rainer
Germany has decided to switch its entire energy supply to renewables in a transition that they have termed as “Energiewende”. A rethinking of industrial production, especially of the chemical production, is the consequence.Organic electrochemistry is thus celebrating a renaissance, since it allows the coupling of renewable energies and chemical production. A highly efficient, sustainable “green chemistry“ with CO2 as the future raw material basis is possible.
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El patrono de los químicos farmacéuticos
(Pontificia Universidad Católica del Perú, 2019-02-20) Rabinovich, Daniel
The focus of this note is Fray Martín de Porres Velásquez, the patron saint of pharmaceutical chemists in Peru, which was portrayed in a Peruvian stamp.
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Artículos científicos de la sección química de la PUCP, 2018 (2a parte)
(Pontificia Universidad Católica del Perú, 2019-02-28) editorial, Comité
Here you will find the first page and the link to all scientific papers published in international journals by members of the PUCP’s Chemistry Section during the second half of 2018.
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Tesis de licenciatura y maestría Sección Química de la PUCP, 2018 (2ª parte)
(Pontificia Universidad Católica del Perú, 2019-04-06) Autores, Varios
Master and "Licenciatura" thesis defended at the chemistry section (PUCP) during the first half of 2018
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La quinina como un símbolo de la química y del Perú
(Pontificia Universidad Católica del Perú, 2019-04-06) Ortega San Martín, Luis
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