Explorando por Autor "Pryor, William"

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El descubrimiento de hidrocarburos aromáticos policíclicos nitrados de estructura inesperada
(Pontificia Universidad Católica del Perú, 1989) Squadrito, Giuseppe; Pryor, William
The reaction mechanism of polyciclic aromatic hydrocarbonsand nitrogen dioxide in solvents of low polarity in vol ves free radicals. The re-action products obtained under these conditions are similar to those found inambient air sarnples, suggesting a common reaction mechanism.
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Investigación sobre la reacción del dioxido de nitrógeno con el fenol
(Pontificia Universidad Católica del Perú, 1989) Fernández Lamarque, María de Fátima; Squadrito, Giuseppe; Pryor, William
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¿Nos encontramos frente a una nueva clase de mutagenos?
(Pontificia Universidad Católica del Perú, 1990) Cuyubamba, Oscar R.; Pryor, William; Shane, Barbara S.; Squadrito, Giuseppe
1,3-Dinitronaphthalene, previous1y identified in particulate organic matter, easily forms covalent adducts with DNA nucleotides at room temperature. The mutagenic potency of a related dinitropolycyclic aromatic hydrocarbon (dinitroPAH) with meta disubstitution, namely 1,3-dinitrofluoranthene, is rather independent of the Salmonella Typhimurium tester strain (TA98, TA98NR and TA98/l, 8DNP6) when assayed according to the Ames Test. This unusual behavior suggests that it does not require metabolic activation via the "classical nitroreductase" and/or the acetylase. The fact that 1,3--dinitronaphthalene readily forms covalent adducts with DNA nucleotides further suggests that dinitroPAH with meta nitro-groups may not require the usual metabolic activation pathways.
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Reactividad del fenol en soluciones acuosas de nitrito de sodio en presencia de micelas de sulfato de dodecilo de sodio
(Pontificia Universidad Católica del Perú, 1991) Squadrito, Giuseppe; Fernández Lamarque, María de Fátima; Pryor, William
The rcactivity of phenol in aqueous solutions containing sodium ni tri te in the prescncc of sodium dodecylsulfate micellcs has bccn studied. Thc reaction yields ortho- and para-nitrophenol, para-nitrosophenol and 2,4-dinitrophenol at low convertions, in yiclds that depend on the pH. The rcsults ha ve been rationalized in terms of a reaction mechanism that involves free radicals.